Hanna Huopio Selected Research

Insulin (Novolin)

11/2013	A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1.
8/2004	Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation.
1/2003	A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1.
1/2002	Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.

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Hanna Huopio Research Topics

Disease

3	Hyperinsulinism (Hyperinsulinemia) 01/2022 - 08/2004
3	Type 2 Diabetes Mellitus (MODY) 01/2018 - 08/2004
3	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2018 - 08/2014
3	Glucose Intolerance 01/2018 - 01/2003
3	Insulin Resistance 08/2014 - 01/2002
3	Congenital Hyperinsulinism 11/2013 - 01/2003
2	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2019 - 12/2018
2	Hypoglycemia (Reactive Hypoglycemia) 08/2004 - 01/2002
1	Obesity 03/2022
1	Down Syndrome (Down's Syndrome) 01/2022
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2022
1	Penis agenesis 12/2018
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2018
1	Inflammation (Inflammations) 01/2018
1	Birth Weight (Birth Weights) 01/2018
1	Body Weight (Weight, Body) 01/2018
1	Prediabetic State (Prediabetes) 01/2018
1	Hyperglycemia 09/2013
1	Seizures (Absence Seizure) 08/2004

Drug/Important Bio-Agent (IBA)

8	Glucose (Dextrose)FDA LinkGeneric 08/2018 - 01/2002
4	Insulin (Novolin)FDA Link 11/2013 - 01/2002
2	Human Follicle Stimulating HormoneIBA 01/2019 - 12/2018
2	Hypoglycemic Agents (Hypoglycemics)IBA 08/2004 - 01/2002
1	Ghrelin ReceptorsIBA 03/2022
1	Antimicrobial PeptidesIBA 03/2022
1	Asparaginase (Elspar)FDA Link 01/2022
1	LipidsIBA 01/2018
1	C-Reactive ProteinIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	Blood Glucose (Blood Sugar)IBA 11/2013
1	KATP ChannelsIBA 11/2013
1	Dihydroxyphenylalanine (Dopa)IBA 01/2006
1	Diazoxide (Hyperstat)FDA Link 08/2004
1	GlucokinaseIBA 08/2004
1	Tolbutamide (Orinase)FDA LinkGeneric 01/2002
1	Adenosine Triphosphate (ATP)IBA 01/2002
1	C-PeptideIBA 01/2002

Therapy/Procedure

1	Caloric Restriction 03/2022
1	Orchiopexy 12/2018
1	Pancreatectomy 08/2004
1	Aftercare (After-Treatment) 08/2004